NIH-funded research R01 grant

Understanding how aging affects the ability to work and finding ways to help.

Official title: Identifying Targets for Interventions to Improve Functional Ability to Work over the Life Course

Funded at Harvard Medical School · NIH-11056765 · Data updated 2026-11-12

This study looks at how getting older affects our ability to work and aims to find ways to help older adults stay active and engaged in their jobs by improving their mental, physical, and social skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard Medical School
NIH-funded
Lab location1 site (Boston, United States)
Project startJune 1, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$598,624
NIH project number5R01AG078301-03
Project IDNIH-11056765 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 65 and older who may be experiencing declines in their functional abilities related to work.

Less likely to help

Patients who are younger than 65 or those who do not have any functional impairments related to work may not benefit from this research.

What this research studies

This research investigates how aging impacts the functional abilities necessary for work, focusing on cognitive, physical, and psychosocial factors. It aims to identify which specific ability losses most significantly affect work capacity and whether public health interventions can prevent or restore these losses. By analyzing data and methods from disability assessments, the project seeks to develop effective, low-cost interventions to improve the work capacity of older adults. Ultimately, the goal is to enhance healthy aging by enabling continued engagement in productive activities.

Why it matters

Potential benefit: If successful, this research could lead to effective interventions that help older adults maintain their ability to work and engage in meaningful activities.

How similar studies have gone: Previous research has shown promise in identifying interventions for maintaining functional abilities in older adults, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Harvard Medical School
    Boston, United States
    Active

Researchers

  • Principal investigator: Maestas, Nicole a — Harvard Medical School
  • Study coordinator: Maestas, Nicole a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.