Understanding how aging affects tendon structure and function
Age-related mechanisms of altered tendon structure and function
['FUNDING_R01'] · UNIVERSITY OF ROCHESTER · NIH-11051186
This study looks at how getting older affects our tendons, which are important for movement and staying active, and aims to find ways to help tendons heal better and stay healthy as we age, so people can enjoy a better quality of life.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-11051186 on ClinicalTrials.gov |
What this research studies
This research investigates how aging leads to changes in tendon structure and function, which can significantly impact mobility and quality of life. The study focuses on the decline in tendon cell density and its effects on the production of essential components that maintain tendon health. By exploring the molecular changes in tendon cells as they age, the research aims to identify strategies to enhance tendon healing and prevent degeneration. Patients may benefit from insights that could lead to improved treatments for tendon injuries related to aging.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing tendon-related issues or injuries.
Not a fit: Patients who are younger and do not have tendon-related problems may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve tendon health and healing in older adults.
How similar studies have performed: Other research has shown promising results in understanding age-related changes in tissues, suggesting potential for success in this area.
Where this research is happening
ROCHESTER, UNITED STATES
- UNIVERSITY OF ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LOISELLE, ALAYNA — UNIVERSITY OF ROCHESTER
- Study coordinator: LOISELLE, ALAYNA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age associated disease, age associated disorder, age dependent disease, age dependent disorder