Understanding how aging affects taste function
The neural basis for aging-dependent decline in taste function
['FUNDING_OTHER'] · FLORIDA STATE UNIVERSITY · NIH-11010403
This study is looking at how getting older affects our sense of taste, using fruit flies to help us understand the changes in the brain that happen with age and how they might connect to diseases like Alzheimer's, so we can learn more about taste loss as we age.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA STATE UNIVERSITY (nih funded) |
| Locations | 1 site (TALLAHASSEE, UNITED STATES) |
| Trial ID | NIH-11010403 on ClinicalTrials.gov |
What this research studies
This research investigates how aging impacts the ability to taste, focusing on the underlying neural mechanisms involved. Using the fruit fly as a model organism, the study explores changes in chemosensory processing that occur with age and how these changes may relate to neurodegenerative diseases like Alzheimer's. The research employs advanced genetic techniques and functional imaging to manipulate and observe taste circuits, aiming to uncover the physiological and molecular factors that contribute to age-related declines in taste perception. By understanding these mechanisms, the research hopes to shed light on broader implications for aging and neurodegeneration.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing changes in taste perception or those at risk for neurodegenerative diseases.
Not a fit: Patients who are not experiencing any taste-related issues or are younger adults may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for taste-related issues in aging populations.
How similar studies have performed: While research on aging and taste perception is limited, studies in related fields have shown promising results in understanding sensory decline associated with aging.
Where this research is happening
TALLAHASSEE, UNITED STATES
- FLORIDA STATE UNIVERSITY — TALLAHASSEE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BROWN, ELIZABETH — FLORIDA STATE UNIVERSITY
- Study coordinator: BROWN, ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.