Understanding how aging affects spatial navigation skills

Behavioral and neural properties of spatial direction comprehension in aging and amestic mild cognitive impairment

NIH-funded research University of Florida · NIH-11004137

This study looks at how getting older and having mild memory issues affect our ability to understand directions, which is important for staying independent, and it compares younger adults with older adults and those with mild cognitive problems to learn more about how our brains work when we navigate.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11004137 on NIH RePORTER

What this research studies

This research investigates how normal aging and mild cognitive impairment impact the ability to comprehend spatial directions, which is crucial for maintaining independence in daily life. The study aims to identify the neural mechanisms involved in spatial direction comprehension by comparing healthy young adults with older adults and those with amnestic mild cognitive impairment. By examining brain connectivity and specific patterns of impairment, the research seeks to enhance our understanding of spatial navigation challenges faced by older adults. The findings could inform the development of targeted interventions to support navigation skills in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults and individuals diagnosed with amnestic mild cognitive impairment.

Not a fit: Patients with severe cognitive impairments or those who do not have age-related cognitive decline may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies and tools that help older adults and those with cognitive impairments navigate their environments more effectively.

How similar studies have performed: Previous research has shown promising results in understanding cognitive decline in aging, suggesting that this approach may yield valuable insights.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age associated neurodegenerative diseaseage associated neurodegenerative disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.