Understanding how aging affects skin cancer development
Epigenetic Regulation of Cutaneous Tumorigenesis
This study is looking at how changes in skin cells as we get older, especially from things like sun exposure, might raise the risk of skin cancer, with the goal of finding better ways to prevent or treat it for older adults.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10890609 on NIH RePORTER |
What this research studies
This research investigates the role of epigenetic changes in skin cells as they age and how these changes may increase the risk of skin cancer. The project focuses on understanding how factors like aging and UV light exposure lead to alterations in the DNA of skin cells, potentially leading to cancer. By studying these changes, the research aims to identify new ways to prevent or treat skin cancer in older adults. Patients may benefit from insights that could lead to improved screening or therapeutic strategies for skin cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are at increased risk for skin cancer due to age and UV exposure.
Not a fit: Patients who are not at risk for skin cancer or who are younger and have no history of UV exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for skin cancer, particularly in older adults.
How similar studies have performed: Previous research has shown promising results in understanding the genetic and epigenetic factors involved in skin cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Chen, David — Washington University
- Study coordinator: Chen, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.