Understanding how aging affects schizophrenia over a person's life
Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11080233
This study is looking at how schizophrenia changes as people get older and aims to find clues in the brain that could help improve treatments for the condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11080233 on ClinicalTrials.gov |
What this research studies
This research investigates the neurobiology of schizophrenia (SZ) across different stages of life, focusing on how aging influences the disease. It aims to identify specific biomarkers that reflect changes in the brain associated with both aging and the progression of schizophrenia. By examining the anterior limbic circuit, the study seeks to uncover distinct biological patterns that could lead to more effective treatments. Patients may be involved in assessments that help clarify the relationship between aging and schizophrenia.
Who could benefit from this research
Good fit: Ideal candidates for participation are adults diagnosed with schizophrenia, particularly those who are experiencing changes related to aging.
Not a fit: Patients who are not diagnosed with schizophrenia or who are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of targeted interventions that improve treatment outcomes for individuals with schizophrenia as they age.
How similar studies have performed: Previous research has shown promise in understanding the neurobiology of mental illnesses, but this approach focusing on the intersection of aging and schizophrenia is relatively novel.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: IVLEVA, ELENA IVANOVNA — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: IVLEVA, ELENA IVANOVNA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.