Understanding how aging affects muscle strength
Motoneuronal mechanisms underlying age-related muscle weakness
['FUNDING_R01'] · OHIO UNIVERSITY ATHENS · NIH-11056056
This study is looking at how changes in nerve cells might make muscles weaker as we get older, and it hopes to find new ways to help older adults stay strong and independent.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO UNIVERSITY ATHENS (nih funded) |
| Locations | 1 site (ATHENS, UNITED STATES) |
| Trial ID | NIH-11056056 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind muscle weakness in older adults, focusing on how changes in motor neurons contribute to this issue. It aims to uncover the role of specific channels in motor neurons that may reduce their ability to activate muscles effectively as people age. By studying these neurological factors, the research seeks to identify new ways to improve muscle strength and function in older individuals, which is crucial for maintaining their independence. The approach combines experimental techniques to assess motor neuron activity and muscle performance in older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who experience muscle weakness or physical limitations.
Not a fit: Patients under the age of 65 or those without any muscle weakness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance muscle strength and reduce physical limitations in older adults.
How similar studies have performed: Previous research has indicated that understanding the neurological aspects of muscle function can lead to significant advancements in treatment for age-related muscle weakness.
Where this research is happening
ATHENS, UNITED STATES
- OHIO UNIVERSITY ATHENS — ATHENS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CLARK, BRIAN C — OHIO UNIVERSITY ATHENS
- Study coordinator: CLARK, BRIAN C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.