Understanding how aging affects muscle health and function
Role of Central Autonomic Relays in Aging Sarcopenia
['FUNDING_R01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-11017759
This study is looking at how the nerves that control our body's automatic functions affect muscle health as we get older, and it aims to find ways to help older adults keep their muscles strong and healthy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-11017759 on ClinicalTrials.gov |
What this research studies
This research investigates the role of the central autonomic nervous system in maintaining muscle health as people age. It focuses on how sympathetic nerves interact with skeletal muscles and how their function declines with age, potentially leading to muscle weakness and loss. By examining the molecular mechanisms involved, the study aims to identify ways to improve muscle function in older adults. Patients may be involved in assessments that help understand these processes better.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who may be experiencing muscle weakness or related health issues.
Not a fit: Patients under the age of 65 or those without any signs of muscle decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance muscle strength and function in older adults, improving their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of sympathetic nerves in muscle health, suggesting that this approach could yield valuable insights.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DELBONO, OSVALDO — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: DELBONO, OSVALDO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.