Understanding how aging affects metabolism through redox regulation
Defining the landscape and mechanisms of redox regulation of metabolism during aging
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-11216701
This study is looking at how changes in certain proteins as we get older affect our metabolism, and it’s for anyone interested in understanding how aging and diet might impact our health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11216701 on ClinicalTrials.gov |
What this research studies
This research investigates how the modification of protein cysteine residues by reactive oxygen species (ROS) influences metabolism as we age. By utilizing advanced proteomics technology, the study aims to identify specific protein changes that occur with aging and caloric restriction. The research also explores the genetic diversity of mouse populations to find potential targets for improving metabolic health in humans. Ultimately, the goal is to uncover mechanisms that could lead to better management of age-related metabolic decline.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing metabolic decline or obesity-related issues.
Not a fit: Patients who are not experiencing age-related metabolic changes or those with unrelated metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving metabolic health and reducing obesity in aging populations.
How similar studies have performed: Previous research has shown promising results in understanding metabolic processes related to aging, suggesting that this approach could yield valuable insights.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XIAO, HAOPENG — STANFORD UNIVERSITY
- Study coordinator: XIAO, HAOPENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.