Understanding how aging affects lung health
Mapping Age-Related Changes in the Lung
['FUNDING_U01'] · OHIO STATE UNIVERSITY · NIH-10473606
This study is looking at how lung cells change as we get older to better understand age-related lung diseases, like idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease, and it’s for anyone interested in how aging affects lung health.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (Columbus, UNITED STATES) |
| Trial ID | NIH-10473606 on ClinicalTrials.gov |
What this research studies
This research investigates the molecular changes in lung cells as people age, focusing on how these changes contribute to age-related lung diseases like idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease. By creating a detailed atlas of aging lung cells, the study aims to identify specific transcriptional differences that may indicate unhealthy aging and contribute to lung dysfunction. The research employs advanced techniques such as single-cell RNA sequencing to analyze the genetic expression of lung cells from both young and older individuals, providing insights into the aging process at a cellular level.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing lung health issues or those interested in understanding the aging process of lung cells.
Not a fit: Patients with acute lung conditions unrelated to aging or those who are not experiencing any lung health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for age-related lung diseases.
How similar studies have performed: Other research has shown promise in understanding cellular aging and its impact on health, making this approach both relevant and potentially impactful.
Where this research is happening
Columbus, UNITED STATES
- OHIO STATE UNIVERSITY — Columbus, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROJAS, MAURICIO — OHIO STATE UNIVERSITY
- Study coordinator: ROJAS, MAURICIO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease