Understanding how aging affects kidney function and blood pressure

Regulation of kidney function and blood pressure in aging

NIH-funded research University of Tennessee Health Sci Ctr · NIH-11063175

This study is looking at how getting older affects kidney health and blood pressure, especially how salt sensitivity plays a role, and it’s for older adults who want to understand more about managing these common health issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Tennessee Health Sci Ctr NIH-funded
Lab location1 site (Memphis, United States)
Project IDNIH-11063175 on NIH RePORTER

What this research studies

This research investigates the relationship between aging, kidney function, and blood pressure, focusing on how salt sensitivity impacts these factors in older adults. The study aims to explore the role of renal stem cell-derived exosomes in maintaining kidney health and regulating blood pressure. By utilizing advanced techniques, researchers will examine whether changes in these exosomes contribute to kidney dysfunction and hypertension associated with aging. This could lead to new insights into managing these common health issues in the elderly.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing kidney issues or high blood pressure.

Not a fit: Patients who are younger and do not have any kidney dysfunction or hypertension may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for kidney dysfunction and hypertension in older adults.

How similar studies have performed: Previous research has shown promising results in understanding the role of exosomes in various health conditions, suggesting potential for success in this area as well.

Where this research is happening

Memphis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.