Understanding how aging affects joint and spinal health
Admin Core
This study is looking at how aging affects our joints and spine, which can make it harder to move and cause pain, and it aims to find ways to help older adults feel better and stay active.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11004724 on NIH RePORTER |
What this research studies
This research investigates the cellular mechanisms that contribute to joint and spinal degeneration as people age, focusing on how these changes can lead to decreased mobility and increased pain. The project aims to establish a supportive infrastructure for interdisciplinary research, which will explore the relationship between cellular aging and the development of frailty in older adults. By examining the role of cellular senescence in joint health, the research seeks to identify potential interventions that could improve quality of life for aging individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing joint pain or mobility issues related to aging.
Not a fit: Patients who are younger and do not have any age-related joint or mobility issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for maintaining mobility and reducing pain in older adults, enhancing their overall quality of life.
How similar studies have performed: Previous research has shown promise in understanding the effects of aging on joint health, indicating that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Cao, Xu — Johns Hopkins University
- Study coordinator: Cao, Xu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.