Understanding how aging affects immune responses in stroke patients
Official title: Characterizing age-related differences in T cell responses to stroke
Funded at Stanford University · NIH-10900059 · Data updated 2026-11-12
This study looks at how age affects the immune response in the brain after a stroke, especially in older adults who may be more likely to develop memory problems, with the goal of finding new ways to help them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 1, 2024 |
| Project end | January 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $42,270 |
| NIH project number | 1F31NS137566-01 |
| Project ID | NIH-10900059 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are elderly individuals who have experienced a stroke and are at risk for vascular dementia.
✕Less likely to help
Patients who are younger or have not experienced a stroke may not benefit from this research.
What this research studies
This research investigates how age influences T cell responses following a stroke, particularly focusing on elderly individuals who are at higher risk for vascular dementia. By using a mouse model, the study aims to characterize the immune response, specifically the behavior of T cells in the brain after a stroke. The researchers will analyze how these immune cells change with age and how they may contribute to cognitive decline in older stroke patients. This work seeks to uncover the mechanisms behind the increased risk of dementia in the elderly after a stroke, potentially leading to new therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for elderly patients at risk of vascular dementia following a stroke.
How similar studies have gone: Previous research has shown significant post-stroke inflammatory responses in aging populations, indicating that this area of study is both relevant and necessary for understanding stroke outcomes.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Jung, Yoo Jin — Stanford University
- Study coordinator: Jung, Yoo Jin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.