Understanding how aging affects immune organs
Yale TMC for Cellular Senescence in Lymphoid Organs
['FUNDING_OTHER'] · YALE UNIVERSITY · NIH-10904912
This study is looking at how aging and stress affect certain immune cells in the body, with the goal of finding ways to help people live healthier and longer lives.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-10904912 on ClinicalTrials.gov |
What this research studies
This research investigates cellular senescence, a process where cells stop dividing, in lymphoid organs that are crucial for immune function. It aims to understand how aging and stress impact these cells and their environments, which could influence overall health and healing. By creating detailed maps of these cellular changes, the research seeks to identify potential strategies to improve healthspan and lifespan. The project involves a multidisciplinary team that will collect and analyze data from human tissues to better understand these processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults or individuals experiencing age-related immune dysfunction.
Not a fit: Patients with acute infections or those who are not experiencing age-related changes in immune function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance immune function and promote healthier aging.
How similar studies have performed: Other research has shown promising results in understanding cellular senescence and its implications for aging, indicating that this approach has potential for success.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FAN, RONG — YALE UNIVERSITY
- Study coordinator: FAN, RONG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.