Understanding how aging affects immune cells in body tissues
Discovering mechanisms of tissue-resident immune aging
This study is looking at how getting older affects the immune cells in our fat tissue and how this might lead to inflammation and health issues, with the goal of finding ways to help older adults stay healthier by improving their immune system and overall well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10472369 on NIH RePORTER |
What this research studies
This research investigates how aging impacts the immune cells that reside in body tissues, particularly focusing on adipose (fat) tissue. It aims to uncover the mechanisms behind age-related inflammation that contributes to chronic diseases in older adults. By utilizing advanced technologies, the study will explore how these immune cells change over time and how they respond to environmental factors like nutrition and stress. The findings could lead to new strategies for improving immune function and metabolic health in the elderly.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing age-related health issues, particularly those with chronic inflammation or metabolic disorders.
Not a fit: Patients who are younger and do not have any age-related immune dysfunction or chronic diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved immune health and reduced chronic disease risk in older adults.
How similar studies have performed: Previous research has shown promising results in understanding immune aging, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Goldberg, Emily Lauren — University of California, San Francisco
- Study coordinator: Goldberg, Emily Lauren
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.