Understanding how aging affects cells in the body
Bioanalysis Core
This study is looking at how certain cells in our bodies stop working properly as we age and how this might affect our health, and it’s designed for anyone interested in understanding aging and age-related diseases better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sanford Burnham Prebys Medical Discovery Institute NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10889159 on NIH RePORTER |
What this research studies
This research investigates cellular senescence, a process where cells stop dividing and release inflammatory factors, which is linked to aging and age-related diseases. The project aims to create a tissue mapping center to identify and characterize senescent cells in various organs, including the brain, bone marrow, breast, colon, and liver of mice. By utilizing advanced single-cell technologies, the researchers will produce detailed maps of these cells, helping to clarify their role in health and disease over a lifespan. This work is crucial for understanding how aging impacts different tissues and could lead to new insights into age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in the biological mechanisms of aging and age-related diseases.
Not a fit: Patients with conditions unrelated to aging or cellular senescence may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential treatments for age-related diseases.
How similar studies have performed: Other research has shown promise in understanding cellular senescence, but this approach is innovative in its use of single-cell technologies for detailed mapping.
Where this research is happening
La Jolla, United States
- Sanford Burnham Prebys Medical Discovery Institute — La Jolla, United States (Active)
Researchers
- Principal investigator: Adams, Peter D. — Sanford Burnham Prebys Medical Discovery Institute
- Study coordinator: Adams, Peter D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.