Understanding how aging affects cancer survivors
Proteomic aging in adults before and after cancer diagnosis
This study is looking at how cancer survivors might age faster than others and wants to create a special tool to measure their biological age using protein levels, which could help predict their health risks and improve their care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10889077 on NIH RePORTER |
What this research studies
This research investigates the phenomenon of accelerated aging in cancer survivors, who often experience age-related diseases earlier than those without a cancer history. By analyzing existing proteomic data from a large population-based cohort, the study aims to construct and validate 'proteomic aging clocks' that can measure biological aging before and after a cancer diagnosis. These clocks utilize sensitive assays to track protein levels over time, providing insights into the relationship between aging, cancer treatment, and chronic inflammation. The goal is to determine whether these aging clocks can predict cancer risk and outcomes, ultimately improving care for cancer survivors.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults who have been diagnosed with cancer and are interested in understanding their aging process and health risks.
Not a fit: Patients who are currently undergoing cancer treatment or those without a history of cancer may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of aging-related health issues in cancer survivors.
How similar studies have performed: Previous research has shown promise in using proteomic data to assess biological aging, but this specific approach in cancer survivors is relatively novel.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Prizment, Anna — University of Minnesota
- Study coordinator: Prizment, Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.