Understanding how aging affects breast cancer spread in the lungs
Adaptations of breast cancer metastasis to the aging lung
This study is looking at how breast cancer cells grow in the lungs of older women and aims to find new ways to treat them better by understanding how aging affects this process.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10910135 on NIH RePORTER |
What this research studies
This research investigates how breast cancer cells adapt and thrive in the lungs of older women, particularly focusing on the unique challenges posed by aging. It aims to uncover the biological mechanisms that allow these cancer cells to metastasize in the lungs, which is crucial for developing more effective treatments. By studying the interaction between cancer cells and the aging lung environment, the research seeks to identify potential therapeutic targets that could improve outcomes for older breast cancer patients. The approach combines cellular biology and aging research to address a significant gap in current cancer treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are older women diagnosed with breast cancer, particularly those experiencing metastasis.
Not a fit: Patients who are younger or do not have breast cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options specifically tailored for older women with breast cancer, potentially reducing mortality rates.
How similar studies have performed: While there has been some research on breast cancer metastasis, the specific focus on aging and its effects on metastasis in the lungs is relatively novel and underexplored.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Da Silva Gomes, Ana — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Da Silva Gomes, Ana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.