Understanding how aging affects breast cancer development
Aging-associated mammary cancer-initiating cells
This study is looking at how certain cells in the breast change as we get older and how these changes might increase the risk of breast cancer, with the goal of finding ways to help prevent it for older adults.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10907537 on NIH RePORTER |
What this research studies
This research investigates the cellular and molecular mechanisms that contribute to the increased risk of breast cancer as people age. By focusing on specific mammary stem cells that are more prevalent in older individuals, the study aims to uncover how these cells may lead to cancerous changes in breast tissue. The researchers will analyze the behavior of these cells in both laboratory settings and animal models to identify potential preventive strategies against age-related breast cancer. This work is crucial as it addresses a significant gap in our understanding of breast cancer risk factors associated with aging.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly women, who are at an increased risk for breast cancer due to age.
Not a fit: Patients who are younger and not at risk for breast cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new prevention strategies for breast cancer in older adults.
How similar studies have performed: Previous research has shown promising results in understanding cancer mechanisms related to aging, suggesting that this approach could yield valuable insights.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: Sun, Luzhe — University of Texas Hlth Science Center
- Study coordinator: Sun, Luzhe
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.