Understanding how aging affects brain networks and memory.
CRCNS: Assessing long-term impacts of disruption to large-scale brain networks
This study is looking at how the brain changes as we get older, especially in people over 65 and those with Alzheimer's, to help understand memory issues and find ways to protect brain health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11083179 on NIH RePORTER |
What this research studies
This research investigates how large-scale brain networks change as people age, particularly focusing on those over 65 years old and individuals with Alzheimer's disease. Using advanced imaging techniques, the study will analyze brain activity during rest to identify patterns that may indicate vulnerability or resilience to cognitive decline. By examining these changes in both humans and mouse models, the research aims to uncover the mechanisms behind age-related memory impairment and Alzheimer's disease. Patients may be monitored for changes in their cognitive abilities and brain function over time.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults aged 65 and above, particularly those experiencing memory issues or diagnosed with Alzheimer's disease.
Not a fit: Patients under 21 years old or those without cognitive decline or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for age-related cognitive decline and Alzheimer's disease.
How similar studies have performed: Previous research has shown promising results in understanding brain network changes related to aging, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Kahn, Itamar — Columbia University Health Sciences
- Study coordinator: Kahn, Itamar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.