Understanding how aging affects brain health in people with schizophrenia spectrum disorders.
Multidimensional aging trajectories in mid to late-life psychosis (MAP)
This study is looking at how getting older affects people with schizophrenia spectrum disorders, especially how their brains change over time, to help find better ways to support their health as they age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11001588 on NIH RePORTER |
What this research studies
This research investigates how aging impacts individuals with schizophrenia spectrum disorders (SSD), focusing on the changes in brain structure and function that may occur as they age. The study aims to fill critical gaps in knowledge about the aging process in SSD by examining brain aging trajectories and identifying potential treatment targets. Using advanced neuroimaging techniques, researchers will analyze the relationship between brain health, cognitive function, and energy metabolism in these patients. The ultimate goal is to develop interventions that could prevent or mitigate the effects of abnormal aging in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with schizophrenia spectrum disorders.
Not a fit: Patients who do not have schizophrenia spectrum disorders or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve brain health and cognitive function in individuals with schizophrenia spectrum disorders as they age.
How similar studies have performed: While the concept of aberrant aging in schizophrenia is emerging, this specific approach using multimodal neuroimaging techniques is relatively novel and has not been extensively tested.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Lee, Junghee — University of Alabama at Birmingham
- Study coordinator: Lee, Junghee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.