Understanding how aging affects behavior in worms
Official title: Inferring multi-scale dynamics underlying behavior in aging C. elegans
Funded at Georgia Institute of Technology · NIH-11015021 · Data updated 2026-11-12
This study looks at how aging affects behavior by observing tiny worms called C. elegans, and it hopes to find new ways to understand aging that could help improve treatments for age-related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | April 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $466,393 |
| NIH project number | 5R01AG082039-03 |
| Project ID | NIH-11015021 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals interested in age-related health issues or those affected by age-associated diseases.
✕Less likely to help
Patients with acute conditions unrelated to aging or those who are not affected by age-related diseases may not receive benefit from this research.
What this research studies
This research investigates the complex processes of aging by studying the behavior of the nematode C. elegans, a model organism. It aims to develop advanced technologies to measure and analyze the dynamics of aging, focusing on how these changes affect behavior over time. By examining the neural origins of these behavioral changes, the research seeks to uncover the connections between short-term actions and long-term health outcomes. Patients may benefit from insights gained about aging processes that could inform future treatments for age-related conditions.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of aging and inform strategies to improve healthspan and longevity in humans.
How similar studies have gone: While this approach is innovative, similar studies in other model organisms have shown promise in understanding aging dynamics.
Where this research is happening
-
Georgia Institute of Technology
Atlanta, United States Active
Researchers
- Principal investigator: Lu, Hang — Georgia Institute of Technology
- Study coordinator: Lu, Hang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.