Understanding how age and sex affect the body's response to cannabis

Age-and sex-dependent pharmacodynamics and pharmacokinetics of oral and smoked delta-9-THC

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10868559

This work explores how different ages and sexes react to cannabis, especially among young adults, older adults, and women.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded)
Locations1 site (LOS ANGELES, UNITED STATES)
Trial IDNIH-10868559 on ClinicalTrials.gov

What this research studies

With cannabis becoming more available, we are seeing more people use it, including groups who might be more sensitive to its effects. This includes young adults (18-25 years old) whose brains are still developing, older adults (55 and up) who experience age-related body changes, and women who may react differently to cannabis than men. This project aims to understand how the body processes and responds to cannabis in these specific groups. By looking at both oral and smoked forms of cannabis, we hope to learn more about how age and sex influence its effects.

Who could benefit from this research

Good fit: Ideal candidates for future related studies would likely include young adults (18-25), older adults (55+), and women who use or are considering using cannabis.

Not a fit: Patients who do not use cannabis or are outside the specified age and sex groups may not directly benefit from this particular research.

Why it matters

Potential benefit: This work could help us better understand the risks and effects of cannabis use for different age groups and sexes, leading to safer guidelines and personalized advice.

How similar studies have performed: This project addresses a gap, as no prior studies have comprehensively looked at the adverse effects of acute THC exposure across these specific adult populations.

Where this research is happening

LOS ANGELES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.