Understanding how adversity influences anxiety and depression in children from low-income backgrounds

Computational examination of RDoC threat and reward constructs in a representative, predominantly low-income, longitudinal sample at increased risk for internalizing disorders (Admin Supplement)

NIH-funded research University of Michigan at Ann Arbor · NIH-10978276

This study is looking at how tough social situations affect anxiety and depression in kids from low-income families, and it aims to find patterns that can help us understand their mental health better as they grow up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10978276 on NIH RePORTER

What this research studies

This research investigates the impact of adverse social conditions on anxiety and depression in children, particularly those from low-income families. By analyzing data from a longitudinal study, researchers will identify patterns of behavior and emotional responses related to threat and reward. The study aims to develop predictive models that can help understand how these factors contribute to mental health issues over time. Participants will be assessed at various stages of their development to track changes and identify risk factors for internalizing disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years from predominantly low-income families, particularly those at risk for internalizing disorders.

Not a fit: Patients who are not within the specified age range or who do not come from low-income backgrounds may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for anxiety and depression in children from disadvantaged backgrounds.

How similar studies have performed: Previous research has shown promising results in understanding the effects of social adversity on mental health, making this approach both relevant and potentially impactful.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.