Understanding how adolescent substance use disorder affects adults

Adult Progression of Adolescent Onset Substance Use Disorder in a High Risk Sample

NIH-funded research University of Colorado Denver · NIH-11085070

This study is looking at what helps or hinders teens who start using substances to either keep using them or stop as they grow into adults, so we can better support those who might be at risk of ongoing substance use.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11085070 on NIH RePORTER

What this research studies

This research investigates the factors that influence whether individuals who began using substances in adolescence continue or stop their substance use as they transition into adulthood. By following a group of adolescents over 18 years, the study aims to identify both risk factors, such as early substance use and genetic vulnerabilities, and protective factors that may help individuals reduce their substance use and associated risky behaviors. The research employs a combination of assessments, including behavioral evaluations and genetic testing, to gain insights into the progression of substance use disorders. This information could help tailor interventions for those at risk of continued substance use.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who began using substances during adolescence and are now transitioning into adulthood.

Not a fit: Patients who have not experienced substance use issues during adolescence may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for individuals struggling with substance use disorders.

How similar studies have performed: Previous research has shown success in understanding the long-term effects of adolescent substance use, making this approach both relevant and promising.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.