Understanding how adolescent alcohol use affects brain circuits
7/8 NADIA U01 Recovery of Adolescent Alcohol Disruption of Basal Forebrain-Cortical Projection Circuits
['FUNDING_U01'] · STATE UNIVERSITY OF NY,BINGHAMTON · NIH-10913315
This study looks at how drinking a lot of alcohol during the teenage years affects the brain's structure and function, and it aims to find ways, like exercise, to help improve brain health for those who have experienced binge drinking.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY OF NY,BINGHAMTON (nih funded) |
| Locations | 1 site (BINGHAMTON, UNITED STATES) |
| Trial ID | NIH-10913315 on ClinicalTrials.gov |
What this research studies
This research investigates the long-term effects of heavy alcohol consumption during adolescence on brain structure and function. It focuses on how binge drinking alters the connectivity of brain circuits that are crucial for cognitive functions. By studying rodent models, the researchers aim to identify the mechanisms behind these changes and explore potential recovery strategies, such as exercise, to reverse the negative impacts on brain health. The goal is to better understand how to restore normal brain function in individuals affected by adolescent alcohol use.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12-20 who have a history of heavy alcohol consumption.
Not a fit: Patients who have not engaged in alcohol use or who are outside the adolescent age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for recovering cognitive functions in adolescents who have experienced alcohol-related brain changes.
How similar studies have performed: Previous research has shown that interventions like exercise can reverse some of the cognitive deficits associated with adolescent alcohol exposure, indicating a promising avenue for recovery.
Where this research is happening
BINGHAMTON, UNITED STATES
- STATE UNIVERSITY OF NY,BINGHAMTON — BINGHAMTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SAVAGE, LISA M — STATE UNIVERSITY OF NY,BINGHAMTON
- Study coordinator: SAVAGE, LISA M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury