Understanding how adenylyl cyclase signaling affects various bodily functions
Regulation of Adenylyl Cyclase Signaling Pathways
This study is looking at how a specific enzyme called adenylyl cyclase helps control important functions in our body and how it can be influenced by other molecules, with the goal of finding better treatments for conditions like heart disease, asthma, and anxiety.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10932136 on NIH RePORTER |
What this research studies
This research investigates the role of adenylyl cyclase (AC) and its product, cyclic AMP, in regulating essential functions across different tissues and organ systems in the body. It focuses on how AC is influenced by G proteins and other regulatory molecules, which are critical for developing new treatments for conditions like heart disease, asthma, and anxiety. By exploring the mechanisms of AC regulation and its signaling specificity, the research aims to uncover how these processes can be manipulated for therapeutic benefits. Patients may benefit from insights that could lead to improved drug therapies targeting these signaling pathways.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals suffering from anxiety disorders, asthma, or cardiac conditions.
Not a fit: Patients with conditions unrelated to adenylyl cyclase signaling or those not experiencing symptoms related to the target conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for a variety of conditions, including anxiety, asthma, and cardiac diseases.
How similar studies have performed: Previous research has shown promising results in targeting adenylyl cyclase signaling pathways for therapeutic purposes, indicating that this approach has potential for success.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Dessauer, Carmen W. — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Dessauer, Carmen W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.