Understanding how acute pancreatitis can lead to type 1 diabetes
Type 1 Diabetes in Acute Pancreatitis Consortium, Pacific Northwest Clinical Center: Immune Pathogenesis of Post-Pancreatitis T1D
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it's for people who have had pancreatitis; researchers will track their health over time to see if diabetes develops and how the immune system plays a role.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Benaroya Research Inst at Virginia Mason NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10897973 on NIH RePORTER |
What this research studies
This research investigates the connection between acute pancreatitis and the development of autoimmune diabetes, specifically type 1 diabetes. By analyzing a large patient population from Virginia Mason Medical Center, the study aims to uncover the incidence, clinical progression, and underlying mechanisms that lead to diabetes following pancreatitis. The research employs both clinical data and biological models to explore how immune responses may contribute to this condition. Patients will be monitored for the development of diabetes and the presence of autoantibodies over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently suffered from acute pancreatitis and are at risk of developing type 1 diabetes.
Not a fit: Patients who have not experienced acute pancreatitis or those with pre-existing type 1 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for type 1 diabetes in patients who have experienced acute pancreatitis.
How similar studies have performed: Previous research has indicated a significant link between acute pancreatitis and the development of diabetes, but this study aims to provide novel insights into the mechanisms involved.
Where this research is happening
Seattle, United States
- Benaroya Research Inst at Virginia Mason — Seattle, United States (Active)
Researchers
- Principal investigator: Greenbaum, Carla J — Benaroya Research Inst at Virginia Mason
- Study coordinator: Greenbaum, Carla J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.