Understanding how actin networks control cell movement in embryos
Dynamic control of actin network architecture in early C. elegans embryos
This study looks at how tiny structures called actin networks help early embryos of the worm C. elegans move and divide, using special imaging techniques to understand how these networks are built and taken apart, which is important for healthy development.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11037566 on NIH RePORTER |
What this research studies
This research investigates the dynamic architecture of actin networks in early C. elegans embryos, focusing on how these networks facilitate essential cellular functions like movement and division. By utilizing advanced microscopy and genetic techniques, the study aims to uncover the mechanisms that regulate the assembly and disassembly of actin filaments in living cells. The research will provide insights into the interplay between actin network structure and cellular dynamics, which is crucial for proper embryonic development.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals interested in the genetic and cellular mechanisms underlying developmental biology.
Not a fit: Patients with conditions unrelated to cellular movement or embryonic development may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of cellular processes that are fundamental to development and may inform treatments for conditions related to cell movement and division.
How similar studies have performed: Other research has shown success in understanding actin dynamics in various cellular contexts, making this approach both relevant and promising.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Munro, Edwin Marshall — University of Chicago
- Study coordinator: Munro, Edwin Marshall
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.