Understanding how actin and microtubules work together in cells
Mechanisms of coordinated actin and microtubule dynamics
This study is looking at how tiny structures in our cells work together, which is important for things like cell division and fixing DNA, and it hopes to find new ways to help people with neurodegenerative disorders by understanding these processes better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Upstate Medical University NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project ID | NIH-10841868 on NIH RePORTER |
What this research studies
This research investigates the coordination of actin filaments and microtubules, which are essential components of the cell's structure. By developing advanced tools to visualize these proteins and their interactions, the research aims to uncover how they regulate critical processes like cell division and DNA repair. The study also explores how these proteins behave in conditions that mimic neurodegenerative disorders, providing insights into their roles in disease. Patients may benefit from a better understanding of cellular mechanisms that could lead to new treatments for various conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurodegenerative disorders or cancers that may be linked to cellular dysfunction.
Not a fit: Patients with conditions unrelated to cellular dynamics or those not experiencing neurodegenerative disorders or cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating neurodegenerative disorders and cancers.
How similar studies have performed: Other research has shown promising results in understanding cytoskeletal dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
Syracuse, United States
- Upstate Medical University — Syracuse, United States (Active)
Researchers
- Principal investigator: Ridilla, Jessica L. — Upstate Medical University
- Study coordinator: Ridilla, Jessica L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.