Understanding how Acinetobacter bacteria survive in the urinary tract
Defining microbial and host determinants of Acinetobacter survival in the urinary tract
This study is looking at how a specific bacteria called Acinetobacter baumannii causes urinary tract infections and why some people are more likely to get these infections, with the hope of finding better treatments for those affected.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10883748 on NIH RePORTER |
What this research studies
This research investigates the factors that allow Acinetobacter baumannii, a type of bacteria, to thrive in the urinary tract, particularly in cases of urinary tract infections (UTIs). The study focuses on identifying both the microbial characteristics of the bacteria and the host factors that make individuals susceptible to these infections. By using a murine model, researchers will explore how different strains of Acinetobacter behave in the urinary system compared to other infections. The goal is to uncover new insights that could lead to better treatment options for patients suffering from multidrug-resistant UTIs.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing recurrent urinary tract infections caused by Acinetobacter baumannii, particularly those with multidrug-resistant strains.
Not a fit: Patients with urinary tract infections caused by other bacteria or those who do not have recurrent infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new, effective treatments for patients with multidrug-resistant urinary tract infections.
How similar studies have performed: Previous research has shown promising results in understanding bacterial behavior in urinary infections, but this specific focus on Acinetobacter baumannii is relatively novel.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Calix, Juan Jose — University of Alabama at Birmingham
- Study coordinator: Calix, Juan Jose
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.