Understanding how abnormal DNA changes contribute to cancer
Research Specialist Support- Establishing and Interpreting Abnormal DNA Methylation in Cancer
This study is looking at how changes in DNA can affect cancer growth, and it aims to find new ways to treat cancer by understanding these changes better, which could help patients in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Van Andel Research Institute NIH-funded |
| Lab location | 1 site (Grand Rapids, United States) |
| Project ID | NIH-10978624 on NIH RePORTER |
What this research studies
This research investigates the role of abnormal DNA methylation in cancer development, focusing on how specific proteins may influence this process. The team, led by Dr. Minmin Liu, utilizes advanced techniques such as next-generation sequencing to analyze genetic and epigenetic changes in cancer cells. By exploring the mechanisms of DNA methylation and its effects on tumor formation, the research aims to uncover new insights that could lead to better cancer treatments. Patients may benefit from this research as it seeks to identify potential biomarkers and therapeutic targets for cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with various types of cancer who are interested in understanding the genetic factors influencing their condition.
Not a fit: Patients with non-cancerous conditions or those not interested in genetic research may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for cancer patients.
How similar studies have performed: Previous research in cancer epigenetics has shown promising results, indicating that understanding DNA methylation can lead to significant advancements in cancer treatment.
Where this research is happening
Grand Rapids, United States
- Van Andel Research Institute — Grand Rapids, United States (Active)
Researchers
- Principal investigator: Liu, Minmin — Van Andel Research Institute
- Study coordinator: Liu, Minmin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.