Understanding how a zinc protein helps maintain brain health
Maintenance of brain homeostasis by an ancient zinc metallochaperone
['FUNDING_CAREER'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-11079666
This study is looking at how a protein called ZNG1 helps keep zinc levels balanced in the brain, which is important for brain health, and it hopes to find new ways to help people with neurological disorders caused by low zinc.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-11079666 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a specific zinc-binding protein, known as ZNG1, in maintaining zinc levels in the brain, which is crucial for various cellular functions. The study aims to understand how zinc deficiency can lead to neurological disorders and how ZNG1 helps deliver zinc to essential proteins in the brain. By exploring the mechanisms of zinc homeostasis, the research seeks to uncover potential therapeutic targets for conditions related to zinc deficiency. Patients may benefit from insights gained about zinc's role in brain health and the development of new treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing neurological issues potentially linked to zinc deficiency.
Not a fit: Patients with neurological disorders not related to zinc deficiency may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neurological disorders associated with zinc deficiency.
How similar studies have performed: Other research has shown promising results in understanding the role of zinc in brain health, indicating that this approach has potential for success.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MURDOCH, CAITLIN CYNTHIA — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: MURDOCH, CAITLIN CYNTHIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.