Understanding how a vitamin A transporter affects vision
Physiological Role of the Vitamin A Transporter RBPR2 for Vision
This study is looking at how a special protein helps move vitamin A in the body, which is important for keeping your vision healthy, especially for people with inherited eye diseases, to find ways to improve their eyesight.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10875533 on NIH RePORTER |
What this research studies
This research investigates the role of a specific vitamin A transporter, RBPR2, in the uptake and transport of dietary vitamin A, which is crucial for maintaining healthy vision. The study aims to understand how this transporter functions in the body and its importance in preventing vision-related issues, particularly in patients with inherited retinal degenerative diseases. By examining the physiological mechanisms of RBPR2, the research seeks to identify potential therapeutic targets that could improve vision by regulating vitamin A levels in the eye. Patients may benefit from insights gained into how vitamin A transport affects their retinal health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with inherited retinal degenerative diseases who may benefit from improved vitamin A transport mechanisms.
Not a fit: Patients with vision problems not related to vitamin A transport or those without retinal degenerative conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve vision in patients with retinal degenerative diseases.
How similar studies have performed: Other research has shown promise in understanding vitamin A transport mechanisms, but this specific investigation into RBPR2 is relatively novel.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Lobo, Glenn P — University of Minnesota
- Study coordinator: Lobo, Glenn P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.