Understanding how a virus replicates in children
Viral and Host Determinants of Parvovirus Replication
This study is looking at how a virus called Human bocavirus 1, which can make young kids sick with respiratory infections, copies itself in the body, and it aims to find ways to help fight this virus and keep children healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-10749895 on NIH RePORTER |
What this research studies
This research investigates how Human bocavirus 1 (HBoV1), a virus that causes respiratory infections in young children, replicates in the body. The study focuses on a specific noncoding RNA produced by the virus that plays a crucial role in its replication process. By using cultured airway cells that mimic natural infections, researchers aim to uncover the mechanisms that allow the virus to thrive and potentially lead to new antiviral treatments. The findings could help in developing strategies to combat infections caused by this virus in children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are experiencing respiratory tract infections.
Not a fit: Patients who are older than 21 years or do not have respiratory infections caused by HBoV1 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for respiratory infections caused by HBoV1 in young children.
How similar studies have performed: Other research has shown success in understanding viral replication mechanisms, making this approach promising but still requiring further exploration.
Where this research is happening
Kansas City, United States
- University of Kansas Medical Center — Kansas City, United States (Active)
Researchers
- Principal investigator: Qiu, Jianming — University of Kansas Medical Center
- Study coordinator: Qiu, Jianming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.