Understanding how a virus causes a common cancer in people with HIV.
(PQ 6) New Models of KSHV Oncogenesis and KS Immune Environment
This study is looking into Kaposi's sarcoma, a type of cancer that affects people with HIV, especially in Sub-Saharan Africa, to find better ways to understand and treat it, which could help improve care for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10832021 on NIH RePORTER |
What this research studies
This research investigates Kaposi's sarcoma (KS), a prevalent cancer among individuals living with HIV, particularly in Sub-Saharan Africa, caused by the Kaposi sarcoma herpesvirus (KSHV). The study aims to develop new models to better understand the disease, including its immune environment and the complex interactions between infected cells and the immune system. By creating preclinical models, the research seeks to explore the mechanisms of KSHV-associated diseases and identify potential therapeutic targets. Patients may benefit from insights gained that could lead to improved treatments for KS and related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Kaposi's sarcoma or those living with HIV who are at risk for KSHV-related cancers.
Not a fit: Patients without HIV or those not affected by KSHV-related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options and outcomes for patients with Kaposi's sarcoma and other KSHV-related diseases.
How similar studies have performed: Previous research has shown promise in understanding KSHV-related diseases, but this approach aims to develop novel models that have not been extensively tested.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Cesarman, Ethel — Weill Medical Coll of Cornell Univ
- Study coordinator: Cesarman, Ethel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.