Understanding how a specific retrovirus affects pregnancy.
The role of the endogenous retroviral family, IAP, in placentation.
This study is looking at how certain natural viruses in our bodies might help with the development of the placenta during pregnancy, using mice to learn more about how they work, which could lead to better understanding of placental health for expecting parents.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10881732 on NIH RePORTER |
What this research studies
This research investigates the role of the IAP family of endogenous retroviruses in the process of placentation, which is crucial for successful pregnancy. By studying how these retroviruses function at the maternal-fetal interface in mice, the research aims to uncover their regulatory roles and potential impacts on fetal development. The methodology includes advanced techniques such as CRISPR and bisulfite sequencing to analyze the genetic and cellular interactions involved. Patients may benefit from insights gained about placental health and its implications for pregnancy outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include pregnant individuals or those planning to conceive, particularly those with a history of placental issues.
Not a fit: Patients who are not pregnant or do not plan to conceive may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of pregnancy-related complications.
How similar studies have performed: Previous research has shown that studying endogenous retroviruses can provide valuable insights into reproductive biology, suggesting potential for success in this area.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Baker, Julie C — Stanford University
- Study coordinator: Baker, Julie C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.