Understanding how a specific protein influences early mammalian development
FUNCTIONAL CHARACTERIZATION OF THE PRDM10-ZN FINGER TRANSCRIPTION FACTOR IN EARLY MAMMALIAN DEVELOPMENT
This study is looking at a protein called PRDM10 to see how it helps control the growth of embryos in early development, which could help us understand more about how babies grow and any related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11084397 on NIH RePORTER |
What this research studies
This research investigates the role of the PRDM10 protein in early mammalian development, focusing on how it regulates gene expression during the critical stages of embryonic growth. By using advanced genetic techniques, the researchers will explore the effects of PRDM10 on embryonic cells and the mechanisms by which it influences development. The study aims to uncover the gene networks that PRDM10 directly regulates, which could provide insights into developmental biology and associated disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a keen interest in developmental biology or those affected by genetic disorders related to early development.
Not a fit: Patients with conditions unrelated to embryonic development or those who are not in the age range of 21+ years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of developmental disorders and potential therapeutic targets for related conditions.
How similar studies have performed: Previous research on other PRDM family proteins has shown promising results in understanding their roles in development, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Guccione, Ernesto — Icahn School of Medicine at Mount Sinai
- Study coordinator: Guccione, Ernesto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.