Understanding how a specific protein affects various diseases
Official title: Regulation of and Target Recognition by Protein Arginine Methyltransferase 1 (PRMT1)
Funded at Utah State University · NIH-10653465 · Data updated 2026-11-12
This study is looking at a protein called PRMT1 to see how it works in diseases like cancer and heart problems, with the hope of finding new ways to treat these conditions by understanding how changes in this protein affect its function.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Utah State University NIH-funded |
| Lab location | 1 site (Logan, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $413,745 |
| NIH project number | 1R15GM150121-01 |
| Project ID | NIH-10653465 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from cancer or cardiovascular diseases.
✕Less likely to help
Patients with conditions unrelated to PRMT1 or those not affected by cancer or cardiovascular diseases may not benefit from this research.
What this research studies
This research investigates the role of Protein Arginine Methyltransferase 1 (PRMT1) in various diseases, including cancer and cardiovascular disorders. It aims to understand how changes in the protein's structure and activity influence its ability to target other proteins within cells. By using advanced techniques to study PRMT1 in living cells, the research seeks to uncover the biochemical mechanisms that regulate this protein's function, which could lead to new treatment strategies. The project will also explore the development of specific inhibitors that can selectively target different forms of PRMT1.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for cancer and other chronic diseases by targeting PRMT1.
How similar studies have gone: Previous research has shown promise in targeting PRMT1 for therapeutic purposes, indicating that this approach could be a meaningful advancement in treatment.
Where this research is happening
-
Utah State University
Logan, United States Active
Researchers
- Principal investigator: Hevel, Joan M — Utah State University
- Study coordinator: Hevel, Joan M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.