Understanding how a specific protein affects various diseases
Regulation of and Target Recognition by Protein Arginine Methyltransferase 1 (PRMT1)
This study is looking at a protein called PRMT1 to see how it works in diseases like cancer and heart problems, with the hope of finding new ways to treat these conditions by understanding how changes in this protein affect its function.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Utah State University NIH-funded |
| Lab location | 1 site (Logan, United States) |
| Project ID | NIH-10653465 on NIH RePORTER |
What this research studies
This research investigates the role of Protein Arginine Methyltransferase 1 (PRMT1) in various diseases, including cancer and cardiovascular disorders. It aims to understand how changes in the protein's structure and activity influence its ability to target other proteins within cells. By using advanced techniques to study PRMT1 in living cells, the research seeks to uncover the biochemical mechanisms that regulate this protein's function, which could lead to new treatment strategies. The project will also explore the development of specific inhibitors that can selectively target different forms of PRMT1.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from cancer or cardiovascular diseases.
Not a fit: Patients with conditions unrelated to PRMT1 or those not affected by cancer or cardiovascular diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for cancer and other chronic diseases by targeting PRMT1.
How similar studies have performed: Previous research has shown promise in targeting PRMT1 for therapeutic purposes, indicating that this approach could be a meaningful advancement in treatment.
Where this research is happening
Logan, United States
- Utah State University — Logan, United States (Active)
Researchers
- Principal investigator: Hevel, Joan M — Utah State University
- Study coordinator: Hevel, Joan M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.