Understanding how a specific protein affects energy balance and obesity
Official title: The Critical Role of Ciliary ARL13B in Controlling Energy Homeostasis
Funded at Emory University · NIH-11082969 · Data updated 2026-11-12
This study is looking at how a protein called ARL13B affects tiny structures in our cells that help control hunger and energy use, with the hope of finding new ways to treat obesity and related health problems.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $81,592 |
| NIH project number | 5F32DK137409-02 |
| Project ID | NIH-11082969 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals struggling with obesity or related metabolic conditions, particularly those with a genetic predisposition to these issues.
✕Less likely to help
Patients who are not affected by obesity or metabolic disorders may not receive any benefit from this research.
What this research studies
This research investigates the role of a protein called ARL13B in cilia, which are tiny structures on cells that help regulate energy balance and feeding behavior. By studying mouse models, the research aims to uncover how disruptions in ciliary signaling can lead to obesity and related health issues. The approach involves examining how these cilia communicate signals that control appetite and energy use, which could lead to new treatment strategies for obesity. Patients may benefit from insights gained into the biological mechanisms of obesity and potential new therapies.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for obesity and related metabolic disorders.
How similar studies have gone: Previous research has shown promising results in understanding ciliary signaling and its impact on obesity, indicating that this approach has potential for success.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Terry, Tiffany T — Emory University
- Study coordinator: Terry, Tiffany T
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.