Understanding how a specific protein affects breast cancer spread
Repression function of FoxM1 in metastasis
This study is looking at how a protein called FoxM1 helps breast cancer spread to other parts of the body, with the goal of finding new ways to stop or slow down that spread for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-10670759 on NIH RePORTER |
What this research studies
This research investigates the role of the FoxM1 protein in the spread of breast cancer to other parts of the body. It aims to uncover the molecular mechanisms that allow tumor cells to metastasize, focusing on how FoxM1 interacts with other proteins to influence cancer progression. By studying these interactions, researchers hope to identify potential targets for new therapies that could prevent or reduce metastasis in breast cancer patients. The approach includes genetic analysis and molecular biology techniques to dissect the functions of FoxM1 in cancer cells.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with aggressive forms of breast cancer, particularly those showing signs of metastasis.
Not a fit: Patients with non-aggressive breast cancer or those whose cancer has not metastasized may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that inhibit the spread of breast cancer, improving survival rates for patients.
How similar studies have performed: Other research has shown promising results in targeting similar molecular pathways in cancer treatment, suggesting that this approach could be effective.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Raychaudhuri, Pradip — University of Illinois at Chicago
- Study coordinator: Raychaudhuri, Pradip
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.