Understanding how a specific protein affects brain development
Official title: Investigating the function of a ciliary protein in neural development
Funded at University of Washington · NIH-11065348 · Data updated 2026-11-12
This study is looking at how a special protein helps brain cells connect with each other, which is really important for how our brains work, and it could help us understand more about brain disorders that affect communication between neurons.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | June 16, 2025 |
| Project end | May 15, 2028 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 1F31NS141228-01 |
| Project ID | NIH-11065348 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with neurodevelopmental or neurodegenerative disorders, particularly those related to synaptic dysfunction.
✕Less likely to help
Patients with conditions unrelated to synapse formation or those not experiencing neurological issues may not benefit from this research.
What this research studies
This research investigates the role of a ciliary protein in the formation of synapses, which are essential for communication between neurons in the brain. By using advanced techniques such as genetics and super-resolution microscopy, the study aims to uncover the molecular mechanisms that regulate synapse formation, particularly in the context of neurological disorders. The research utilizes the model organism C. elegans to explore how this protein interacts with known regulators of nervous system development. The findings could provide insights into neurodevelopmental and neurodegenerative disorders.
Why it matters
Potential benefit: If successful, this research could lead to new understanding and potential treatments for neurological disorders related to synapse formation.
How similar studies have gone: Other research has shown success in understanding synapse formation and its implications for neurological disorders, making this approach promising.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Ayala, Nelson Andy — University of Washington
- Study coordinator: Ayala, Nelson Andy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.