Understanding how a specific potassium channel affects recovery from spinal cord injuries

Who could benefit from this research

What this research studies

This research investigates the role of the kcnn1 gene, which encodes a potassium channel, in the recovery process following spinal cord injuries. Using zebrafish models, the researchers will create genetically modified fish to study how changes in kcnn1 expression influence spinal cord development and recovery. They will also explore the effects of a potassium channel inhibitor, 4-aminopyridine, to see if it can enhance recovery outcomes. The ultimate goal is to identify potential therapeutic strategies for spinal cord injuries and related neurological conditions.

Why it matters

Where this research is happening

• East Carolina University
  Greenville, United States Active

Researchers

• Principal investigator: Mruk, Karen — East Carolina University
• Study coordinator: Mruk, Karen

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.