Understanding how a specific brain pathway affects walking after a stroke.

Elucidating the role of the contralesional corticoreticulospinal tract for lower limb function after stroke.

NIH-funded research University of Illinois at Chicago · NIH-10782552

This study is looking at how a specific brain pathway can help people who have had a stroke improve their walking abilities, with the hope of finding better ways to support their recovery and independence.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-10782552 on NIH RePORTER

What this research studies

This research investigates the role of the corticoreticulospinal tract, a brain pathway, in improving lower limb function for individuals who have experienced a stroke. The study aims to identify how this pathway from the non-affected side of the brain can be enhanced to support recovery of walking abilities. By using advanced measurement tools, researchers will assess the functionality of this pathway and its influence on motor control of the affected limb. The ultimate goal is to improve rehabilitation strategies for stroke survivors, helping them regain independence in mobility.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a stroke and are facing challenges with walking and lower limb function.

Not a fit: Patients who have not had a stroke or those with severe cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective rehabilitation techniques that enhance walking recovery for stroke patients.

How similar studies have performed: Previous research has shown promise in enhancing motor pathways for stroke recovery, indicating that this approach could yield significant insights.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Gait disorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.