Understanding how a specific brain area regulates body weight and metabolism

PERIFORNICAL AREA OF THE ANTERIOR HYPOTHALAMUS REGULATES METABOLIC BALANCE

NIH-funded research Baylor College of Medicine · NIH-10992553

This study is looking at a specific part of the brain in mice to see how it helps control hunger and energy use, which could help us find new ways to treat obesity.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionBaylor College of Medicine NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10992553 on NIH RePORTER

What this research studies

This research investigates the role of the perifornical area of the anterior hypothalamus in regulating energy balance and metabolism, particularly in the context of obesity. By studying mice, the researchers aim to understand how certain structures in this brain region influence appetite and energy expenditure. They will employ various techniques, including genetic and pharmacological methods, to explore how disruptions in these structures affect weight gain and fat accumulation. The ultimate goal is to uncover mechanisms that could lead to new treatments for obesity.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals, particularly children and adults, who are affected by obesity or related metabolic disorders.

Not a fit: Patients who are not experiencing issues with weight management or metabolic balance may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing and treating obesity, benefiting patients struggling with weight management.

How similar studies have performed: Previous research has shown promising results in understanding the role of the hypothalamus in energy regulation, suggesting that this approach could yield valuable insights.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.