Understanding how a specific bacteria contributes to gum disease
Characterization of Selenomonas sputigena pathogenesis
['FUNDING_R03'] · VIRGINIA COMMONWEALTH UNIVERSITY · NIH-10810907
This study is looking at a specific bacteria called Selenomonas sputigena, which is connected to gum disease, to see how it causes inflammation and damage in your mouth, and how it interacts with gum cells and other bacteria.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VIRGINIA COMMONWEALTH UNIVERSITY (nih funded) |
| Locations | 1 site (RICHMOND, UNITED STATES) |
| Trial ID | NIH-10810907 on ClinicalTrials.gov |
What this research studies
This research investigates the role of Selenomonas sputigena, a type of bacteria linked to gum disease, in causing inflammation and tissue damage in the mouth. The study aims to understand how this bacteria interacts with gum cells and other bacteria, and how it may evade the immune response. By examining the bacteria's movement and ability to form biofilms, the research seeks to uncover its pathogenic properties and their implications for periodontal disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from periodontal disease or those with high levels of Selenomonas sputigena in their oral microbiome.
Not a fit: Patients without periodontal disease or those who do not harbor Selenomonas sputigena may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for periodontal disease by targeting the mechanisms of Selenomonas sputigena.
How similar studies have performed: While the specific pathogenic mechanisms of Selenomonas sputigena are not well-studied, similar research on other periodontal bacteria has shown promising results in understanding their role in gum disease.
Where this research is happening
RICHMOND, UNITED STATES
- VIRGINIA COMMONWEALTH UNIVERSITY — RICHMOND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MILLER, DANIEL PATRICK — VIRGINIA COMMONWEALTH UNIVERSITY
- Study coordinator: MILLER, DANIEL PATRICK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.