Understanding how a protein helps gut cells divide and repair
Official title: Control of Drosophila intestinal homeostasis by RhoGap15b
Funded at Emory University · NIH-11170830 · Data updated 2026-11-12
This study is looking at how a certain protein helps control cell division in the gut, especially when it’s healing, and it’s for anyone interested in understanding how our bodies keep our gut healthy as we age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $381,022 |
| NIH project number | 1R56AG085250-01A1 |
| Project ID | NIH-11170830 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in gut health, particularly those with conditions affecting gut tissue repair.
✕Less likely to help
Patients with no interest in gut health or those not experiencing issues related to gut tissue repair may not benefit from this research.
What this research studies
This research investigates how a specific protein, conserved from fruit flies to humans, regulates cell division in the gut, particularly during tissue repair. By studying the role of this protein in Drosophila, the researchers aim to uncover mechanisms that support stem cell renewal in the gut over an organism's lifespan. The approach involves analyzing how this protein interacts with various signaling pathways that are crucial for maintaining gut health. The findings could provide insights into similar processes in human gut cells.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing gut health and repairing damaged tissues in patients.
How similar studies have gone: Other research has shown success in understanding similar proteins and their roles in cell division and tissue repair, indicating that this approach is promising.
Where this research is happening
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Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Moberg, Kenneth H — Emory University
- Study coordinator: Moberg, Kenneth H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.