Understanding how a protein affects gum health and healing
The Role of Bone Sialoprotein in Modulating Periodontal Development and Repair
This study is looking at how a protein called bone sialoprotein helps with the healing of gums and teeth, which could lead to better treatments for people dealing with gum disease.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10889973 on NIH RePORTER |
What this research studies
This research investigates the role of bone sialoprotein in the development and repair of periodontal tissues, which are crucial for maintaining healthy teeth and gums. By studying how this protein influences the healing process in the mouth, the research aims to uncover new insights into periodontal disease, which affects a significant portion of adults. The approach includes examining the effects of bone sialoprotein in animal models to understand its impact on bone and tissue health. This could lead to improved therapies for those suffering from periodontal disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 30 and older who are experiencing periodontal disease or related dental issues.
Not a fit: Patients with healthy gums and no history of periodontal disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for periodontal disease, improving oral health and quality of life for patients.
How similar studies have performed: Previous research has shown promising results in understanding the role of proteins in bone and tissue health, suggesting potential for success in this area as well.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Andras, Natalie Lynn — Ohio State University
- Study coordinator: Andras, Natalie Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.