Understanding how a protein affects fat storage in cells
Discovering the new function of DRP1 on lipid metabolism
This study is looking at how a protein called DRP1 helps our cells create and manage fat storage, which is important for keeping our energy levels balanced, and it's for anyone interested in understanding how our bodies handle fat.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11064786 on NIH RePORTER |
What this research studies
This research investigates the role of dynamin-related protein 1 (DRP1) in the formation and regulation of lipid droplets, which are essential for energy storage in cells. The study aims to uncover the molecular mechanisms by which DRP1 influences the budding of lipid droplets from the endoplasmic reticulum, a critical process for maintaining metabolic balance. Researchers will utilize both laboratory and living cell models to explore how DRP1's activity is regulated and its impact on lipid metabolism. By understanding these processes, the research seeks to provide insights into how fat storage is controlled in the body.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with metabolic disorders, particularly those related to fat metabolism and obesity.
Not a fit: Patients who do not have metabolic disorders or conditions related to lipid metabolism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing obesity and related metabolic disorders.
How similar studies have performed: Previous research has shown promising results in understanding lipid metabolism, but the specific role of DRP1 in this context is still being explored.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Sun, Kai — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Sun, Kai
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.