Understanding how a parasite affects the immune response in women
Official title: Elucidating the role of IFN epsilon mediated type I IFN responses against Trichomonas vaginalis
Funded at University of California Los Angeles · NIH-10998491 · Data updated 2026-11-12
This study is looking at how the Trichomonas vaginalis parasite, which causes trichomoniasis, affects the immune system in women, especially those who are nearing or past menopause, to find better ways to prevent health problems linked to this infection.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $76,784 |
| NIH project number | 1F32AI186416-01 |
| Project ID | NIH-10998491 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women, particularly those who are peri- or post-menopausal, who may be experiencing or at risk for trichomoniasis.
✕Less likely to help
Patients who are not female or who do not have a history of trichomoniasis may not benefit from this research.
What this research studies
This research investigates the protozoan parasite Trichomonas vaginalis, which causes the common sexually transmitted infection trichomoniasis. The focus is on how this parasite interacts with the immune system, particularly in the female reproductive tract, and how it may contribute to serious health issues like increased susceptibility to HIV and reproductive complications. The study aims to explore the mechanisms by which the parasite alters immune responses and promotes its own survival, especially in women who are peri- or post-menopausal. By examining the immune environment and the role of immune cells, the research seeks to uncover new strategies for preventing the negative health impacts associated with this infection.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for women affected by trichomoniasis and its associated health risks.
How similar studies have gone: Previous research has shown promising results in understanding immune responses to similar infections, indicating that this approach may yield valuable insights.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Kochanowsky, Joshua Andrew — University of California Los Angeles
- Study coordinator: Kochanowsky, Joshua Andrew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.